Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction.
Progressive renal disease is characterized by tubulo-interstitial injury with ongoing inflammation and fibrosis.The Nlrp3 inflammasome contributes to these pathophysiological processes through Retinol its canonical effects in cytokine maturation.Nlrp3 may additionally exert inflammasome-independent effects following tissue injury.Hence, in this stu